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Hongkong Yuancheng Saichuang Technology Co., Ltd.

Lidocaine, Lidocaine Base, Xylocaine manufacturer / supplier in China, offering 99% Purity and Good Quality Anti-Paining Anesthetics Lidocaine, New Product Peptide Myostatin 85 Powder for Muscle Growth 1mg/Vial, High Quality Peptide Tb500 Thymosin Beta 4 for Muscle Building and so on.

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Supplier Homepage Product Local Anesthetic Powders 99% Purity and Good Quality Anti-Paining Anesthetics Lidocaine

99% Purity and Good Quality Anti-Paining Anesthetics Lidocaine

FOB Price: US $1 / kg
Min. Order: 1 kg
Min. Order FOB Price
1 kg US $1/ kg
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Port: Shenzhen, China
Production Capacity: 10000kg
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: 99%
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Mf: C14h23n2o58
  • Reference Standard: Bp2002/USP28
  • Trademark: YC
  • Specification: 99%
  • HS Code: 2924299090
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP
  • State: Solid
  • CAS No: 137-58-6
  • MW: 235.3447
  • Character: White Crystalline Powder
  • Transport Package: 25kg/Drum
  • Origin: China
Product Description
99% purity and good quality Anti-Paining Anesthetics Lidocaine



Basic info

Product Name: Lidocaine Base
Synonyms: 2-(Diethylamino)-N-(2, 6-dimethylphenyl)-acetamide; Lignocaine; 2-diethylaminoacet-2, 6-xylidide; Lidocaine; Xylocaine; N-(2, 6-dimethylphenyl)-N~2~, N~2~-diethylglycinamide; 2-[(2, 6-dimethylphenyl)amino]-N, N-diethyl-2-oxoethanaminium
CAS Registry Number: 137-58-6
Assays: 99%
Packaging: 25kg/drum
Molecular Formula: C14H23N2O
Molecular Weight: 235.3447
EINECS: 205-302-8
Appearance: White crystal
HS: 2924299090
Property: Soluble in ethanol, ether, benzene, chloroform and oil, insoluble in water.
Package: 25kg/drum

Product Description

Character: White crystalline powder
Usage: It replaces procaine, being widely used in plastic and cosmetic operation in local infiltration anesthesia, the sodium channel inhibition of the nerve cell membrane to block nerve excitability and conduction.
Mechanism of action: Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.
Hemodynamics: Excessive blood levels may cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. With central neural blockade these changes may be attributable to block of autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system and/or the beta-adrenergic receptor stimulating action of epinephrine when present. The net effect is normally a modest hypotension when the recommended dosages are not exceeded.

Applications:

Lidocaine crosses the blood-brain and placental barriers, presumably by passive diffusion.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine. Approximately 90% of Lidocaine administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2, 6-dimethylaniline.

COA:

Test Items
 

Standard
 

Result
 

Appearance
 

White or almost white crystalline powder
 

White crystalline powder
 

Identification
 

(1)
 

Infrared absorption spectrum of the substance is same as that of Lidocaine Intermediate CRS
 

Complies with the requirement
 

(2)
 

Melting point: 66~70
 

66~68.5
 

(3)
 

Complies with the requirement
 

Complies with the requirement
 

Related substance
 

Complies with the requirement
 

Complies with the requirement
 

Chlorides
 

≤35ppm
 

<35ppm
 

Sulphates
 

≤0.1%
 

<0.1%
 

Water
 

≤1.0%
 

0.27%
 

Sulphated ash
 

≤0.1%
 

0.01%
 

Assay
 

99.0%~101.0%

(anhydrous substance, C14H22N2O)
 

99.41%
 
 
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