Estradiol Benzoate (CAS 50-50-0)
Synonym: 17β-Estradiol 3-Benzoate
Application: A steroid used for biological research purposes
CAS Number: 50-50-0
Molecular Weight: 376.49
Molecular Formula: C25H28O3
Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol.
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