98% Purity Pharmaceutical Raw Material Spironolacton 52-01-7
|FOB Price:||US $1 / gram|
|Min. Order:||1 gram|
|Min. Order||FOB Price|
|1 gram||US $1/ gram|
|Port:||Hong Kong, Hong Kong|
|Production Capacity:||500 Tons/Month|
|Payment Terms:||L/C, T/T, D/P, Western Union, Paypal, Money Gram|
- Model NO.: 52-01-7
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- Color: White
- Trademark: Saichuang
- Specification: Qualified
- HS Code: 2901100000
- Powder: Yes
- Certification: ISO 9001, USP, BP
- State: Solid
- Form: Crystalline Solid
- CAS: 52-01-7
- Transport Package: Disguise
- Origin: China
mp 207-208 °C(lit.)
alpha -37 º (c=1, CHCl3)
refractive index -36 ° (C=1, CHCl3)
storage temp. Store at RT
Water Solubility practically insoluble
Chemical Properties White to Off White Solid
Usage It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia
Usage diuretic, aldosterone antagonist
Biological Activity Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis.
Product Categories: Active Pharmaceutical Ingredients;Biochemistry;Steroids;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;API's;ALDACTONE
Synonyms: (7alpha,17alpha)-;17alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7alpha-mercapto-3-oxo-, gamma-lactone, acetate;17-alpha-Pregn-4-ene-21-carboxylic acid, 1-hydroxy-7-alpha-mercapto-3-oxo-alpha-lactone;17-alpha-pregn-4-ene-21-carboxylicacid,1-hydroxy-7-alpha-mercapto-3-oxo-alpha;17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid gamma-lactone acetate;17-hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylicaciga;17-hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylicacigamm;3-(3-keto-7-alpha-acetylthio-17-beta-hydroxy-4-androsten-17-alpha-yl)propion
Spironolacton (INN, BAN, USAN), marketed mainly under the brand name Aldactone in most countries, is a synthetic, steroidal antimineralocorticoid, as well as, to a lesser extent, an antiandrogen, progestin, and antigonadotropin. It belongs to a class of drugs known as potassium-sparing diuretics, and is used primarily as a diuretic and antihypertensive in the treatment of heart failure and hypertension. As a secondary use, spironolacton is also frequently employed off-label for the purpose of reducing androgen levels and activity in the body, such as in the treatment of hyperandrogenism in women and as a component of hormone replacement therapy for trans women.
Spironolacton is a relatively old drug, having been introduced clinically in 1959. Futterman and Lemberg predicted that spironolactone will be less commonly used in cardiovascular conditions as newer agents such as eplerenone are more selective and produce fewer side effects - namely, antiandrogenic side effects. However, spironolacton remains widely used for indications in which its antiandrogen effects are the intention of treatment.
Spironolacton is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Tag: china raw steroid powder supplier, steroid hormone manufacturer
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