Anti - Pain Local Anesthetic Levobupivacaine Hydrochloride CAS 27262-48-2
|FOB Price:||US $1 / grams|
|Min. Order:||10 grams|
|Min. Order||FOB Price|
|10 grams||US $1/ grams|
|Port:||Hong Kong, Hong Kong|
|Payment Terms:||T/T, Western Union, Paypal, Money Gram, Bitcoin|
- Model NO.: 27262-48-2
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- CAS: 27262-48-2
- Trademark: Saichuang
- Specification: qualified
- HS Code: 3001200010
- Powder: Yes
- Certification: GMP, ISO 9001
- State: Solid
- Name: Levobupivacaine Hydrochloride
- Assay: >99%
- Transport Package: Discreet
- Origin: China
--- Local Anesthetic Drugs Basic Information ---
|Product name||Levobupivacaine hydrochloride|
|Other name||2-Piperidinecarboxamide,1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride, (2S)- (9CI); 2-Piperidinecarboxamide|
|Appearance||White Crystalline Powder|
|Product categories||Local Anesthetic Drugs ; Active pharmaceutical ingredients|
--- Local Anesthetic Drugs Description ---
Levobupivacaine hydrochloride is a sodium channel blocker used as a long-acting local anaesthetic for epidural anesthesia . Levobupivacaine is the isomer of bupivacaine , with efficacy similar to that of bupivacaine with a reduced risk of cardiotoxicity .
Levobupivacaine Hydrochloride is the hydrochloride salt of levobupivacaine , an amide derivative with anesthetic property . Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses , thereby resulting in analgesia and anesthesia .
In comparison with racemic bupivacaine , levobupivacaine is associated with less vasodilation and has a longer duration of action .
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.
Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium.
This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.
The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.
Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.
--- Packaging & Delivery ---
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