Cjc-1295 Without Dac Peptides Mod Grf 1-29 Releasing Raw Powder
|FOB Price:||US $1 / grams|
|Min. Order:||10 grams|
|Min. Order||FOB Price|
|10 grams||US $1/ grams|
|Port:||Hong Kong, Hong Kong|
|Production Capacity:||500 Tons/Month|
|Payment Terms:||T/T, D/P, Western Union, Paypal, Money Gram, Bitcoin|
- Model NO.: Cjc-1295
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- MW: 3367.2
- Transport Package: Accoding to Every Customers′ Requirements
- Origin: China
- Powder: Yes
- Certification: GMP, ISO 9001
- State: Liquid
- Mf: C152h252n44o42
- Trademark: Saichuang
- Specification: qualified
- HS Code: 3001200010
Synonyms: CJC-1295 without DAC, CJC 1295 w/o DAC, MOD GRF 1-29, Neorelin, Modified Sermorelin
Molecular Formula: C152H252N44O42
Molecular weight: 3367.2
Molar Mass: 3368.7
Peptide purity: > 99.0%
Appearance: White lyophilized powder
Related substance: Total Impurities (%) ≤ 2.0%
Acetate content: ≤ 15.0%
Bacterial Endotoxins: ≤5 IU/mg
Source: Chemical Synthesis
Reconstitution: To follow best practice guidelines for reconstituting CJC-1295 without DAC, reconstitute in sterile, bacteriostatic, distilled water, with light sonication if necessary.
Storage for MOD GRF 1-29: Lyophilized MOD GRF 1-29 is stable at room temperature for 90 days, however it should be stored in a freezer below -8°C for any extended period of time. After reconstitution, may be stored for a maximum of 14 days in a refrigerator at 2°C - 8°C. Store vials in an upright position. Store MOD GRF-129 refrigerated between temperatures 2°C - 8°C. Keep in the outer carton in order to protect from light. For one month can be stored at room temperature.
Shelf life: One year from dispatch.
What is CJC-1295 without DAC and used for?
Modified GRF 1-29 is also known as Mod GRF 1-29, but even more commonly known as CJC-1295 without DAC. It is a protein that is 29 amino acids long and it is a GHRH analogue. CJC-1295 without DAC acts on receptors at the pituitary gland to stimulate the release of Human Growth Hormone.
CJC-1295 without DAC could be referred to more properly as a second generation derivative of GHRH. GHRH is modified to create what is known as Releasing Factor (GRF) 1-29, also known as Sermorelin. GRF 1-29 is then further modified to create Mod GRF 1-29 which is CJC-1295 without DAC.
Application & More information for CJC-1295 without DAC
Releasing Hormone (GHRH), which is the endogenously secreted GHRH by the arcuate nucleus of the hypothalamus of the human body, is 44 amino acids long. It was discovered, however, that only the first 29 amino acids of the protein were equally as effective in binding to receptors on the pituitary gland as the full 44 amino acid structure. The first 29 amino acids in its protein structure were then isolated, which was then called GRF 1-29, but the problem with this derivative of GHRH was the fact that it was rapidly metabolized and cleared from the body by enzymes. S
Therefore, the solution to this was to modify GRF 1-29 by replacing various amino acids in its structure with other amino acids that would provide a greater resistance to breakdown and cleavage by enzymes. There were many modified analogues developed, and Mod GRF 1-29 (CJC-1295 without DAC) was eventually selected for use, which demonstrated the most promising effects. Mod GRF 1-29 is a modification of GRF 1-29, specifically at amino acids #2, #8, #15, and #27. The result is an extended half-life to that of at least 30 minutes.
Mod GRF 1-29 acts upon receptors located in the anterior pituitary gland, and signals the pituitary gland to increase Human production and cause a release of massive quantities of Human Hormone in a pulsatile manner. Therefore, multiple applications of Mod GRF 1-29 is recommended throughout the day in order to simulate Human Growth Hormone levels that remain high on a constant basis. Mod GRF 1-29 (CJC-1295 without DAC) is commonly combined with a Ghrelin mimetic (also known as a GHRP - Releasing Hexapeptide), such as GHRP-6, GHRP-2, Hexarelin, or Ipamorelin in order to initiate and amplify a greater pulse from the pituitary compared to Mod GRF 1-29 used solitarily on its own.
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