Pharma Grade Topical Local Anesthetic Drug Tetracaine Hydrochloride Tetracaine
|10-499 500-999 1,000+|
|FOB Unit Price:||US $1.2 US $1 US $0.8|
|Purchase Qty. (g)||FOB Unit Price|
|Production Capacity:||Mass Stock|
|Payment Terms:||L/C, T/T, Western Union, Money Gram, Bitcoin,Bank Transfer|
- Model NO.: CAS 94-24-6
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- Synonyms: Amethocaine
- Einecs: 202-316-6
- Storge: in Cool and Dry Condition
- Transport Package: 25kg/Drum
- Origin: China
- Powder: Yes
- Certification: GMP, HSE, ISO 9001, USP, BP
- State: Solid
- Product: Tetracaine
- CAS: 94-24-6
- Appearance: White Powder
- Trademark: Saichuang
- Specification: ISO 9001
- HS Code: 3002901000
|Appearance||White crystalline powder|
|Usage||Tetracaine is a topical local anesthetic for the eyes. Tetracaine works by interfering with entry of sodium ions into nerve cells. This reduces the ability of nerves to generate an impulse and send pain sensations.|
(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000), and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. A systematic review and meta-analysis of randomised controlled trials investigated tetracaine for use in emergency departments, especially for IV cannulation in children, in view of its analgesic and cost-saving properties - however it did not find a statistically significant improvement in first attempt cannulations.
1. Local anesthetics.
2. Local anesthetic toxicity is greater, Be Proulx Kain, through the mucosa, mainly used for mucosa anesthesia.
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